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a16z is a venture capital firm that invests in software eating the world. Each week, we share videos on technology trends and advice for building companies. The views expressed here are those of the individual personnel quoted and are not the views of a16z or its affiliates. This content is provided for informational purposes only, and should not be relied upon as legal, business, investment, or tax advice. Furthermore, this content is not directed at nor intended for use by any investors or prospective investors and may not under any circumstances be relied upon when making a decision to invest in any a16z funds. PLEASE SEE MORE HERE: https://a16z.com/disclosures/

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Science & Tech

The New Rules of Media | Marc Andreessen & Ben Horowitz

This episode features Marc Andreessen and Ben Horowitz, co-founders of venture firm Andreessen Horowitz (a16z), joined by Gabby Ben-Amor and host Eric, recorded live at the New Media Summit. The conve…

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Science & Tech

The Fintech Playbook for Latin America

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Science & Tech

Jack Altman on Product-Market Fit

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AI, Design, and the Power of Open Models

Yuka Lee and Justine Moore speak with Mohammad Norouzi, CEO and founder of Ideogram, a Toronto-based generative AI company that just released their first open-weight image generation model. The conver…

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Science & Tech

Samo Burja on Growth, Energy, and AI

Samo Burja, founder of Bismarck Analysis, joins host Theo Jaffe to discuss how AI's massive infrastructure demands are triggering the first industrial revolution in decades. The conversation explores …

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Science & Tech

Designing the Physical World with AI

A16z general partner Aaron Price-Wright speaks with Alex Bowden, co-founder and CEO at Unlimited Industries, and Davide Asnaghi, CEO at Diode Computers. Alex's company uses AI to vertically integrate …

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Science & Tech

How Superhuman Took Over Silicon Valley Email

Rahul Vohra is the founder and CEO of Superhuman, previously acquired by Grammarly in 2025. He holds a computer science degree from Cambridge and started his career as a game designer at Jagex working…

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Science & Tech

Marc Andreessen on AI, California, and the Future of America | Joe Rogan

Marc Andreessen, co-founder of Andreessen Horowitz and Netscape, discusses the transformative potential of artificial intelligence with Joe Rogan. Andreessen argues that AI represents the most revolut…

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Science & Tech

Rebuilding The American Shipyard

Michael Duffy, Deputy Assistant Secretary of Defense, speaks with Dino Mavroukis, founder of Sauronic, about rebuilding America's defense industrial base through autonomous systems and modern manufact…

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The Plan to Make American Crime Obsolete

Colonel Jeffrey Glover from Arizona Department of Public Safety and Rahul Sidhu, co-founder of Flock Safety, discuss the technological transformation of American law enforcement with host David Ulevic…

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Vitalik Buterin on Human Agency in the AI Era

Sophia Du and Bingi Pandey speak with Vitalik Buterin, founder of Ethereum and prominent technology thinker, about human agency, sanctuary technologies, and the future of decentralized systems. The co…

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Science & Tech

Ben Horowitz - "Your ONLY job is Right Product, Right Time"

Ben Horowitz, co-founder of Andreessen Horowitz, speaks at A16Z's Speedrun event about the fundamentals of building successful companies. Despite being a venture capitalist now, Horowitz draws from hi…

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Science & Tech

Energy, Minerals, and the Physical Stack Behind AI

Turner Caldwell, co-founder and CEO of Mariana Minerals, and Drew Baglino, founder and CEO of Heron Power, both spent extensive time at Tesla building critical infrastructure. Caldwell led Tesla's min…

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Science & Tech

Lloyd Blankfein on Risk, Crisis, and Leadership

Lloyd Blankfein, former CEO and Chairman of Goldman Sachs, speaks with A16Z general partner David Haber about leadership, risk management, and navigating uncertainty. Blankfein led Goldman through mul…

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Science & Tech

Marc Andreessen on Builder Culture in the Age of AI

Mark Andreessen, co-founder of Andreessen Horowitz, joins Eric Newcomer to discuss the rapidly evolving AI landscape and its broader implications for society, work, and institutions. The conversation …

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Ben Horowitz on the Next Technology Era

Ben Horowitz, co-founder of Andreessen Horowitz (A16Z), speaks with general partner David Ulevitch about venture capital's role in maintaining American technological leadership. The conversation takes…

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Crypto Fund 5: We Raised $2.2B. Here’s Why.

A16Z Crypto announces Fund 5 with all general partners: founder and managing partner Chris Dixon, general partner Ali Yahya (former Google Brain researcher), newly promoted general partner Eddie Lazar…

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Science & Tech

The New Space Race: NASA, Artemis, and the Race to the Moon

NASA Administrator Jared Isaacman speaks with Morgan Brennan at the A16Z American Dynamism Summit about America's return to the moon and the new space race dynamics. Isaacman, who took office recently…

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Building Blackstone, Backing Costco, with Tony James

Tony James traces a remarkable career building enduring financial institutions across three decades. From joining DLJ as an investment banking associate in 1975 when it was a "sub-sub-major firm" that…

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Science & Tech

Balaji and Taylor Lorenz on AI and Media

Theo Jaffe hosts a conversation between Balaji Srinivasan, former Coinbase CTO and network state advocate, and Taylor Lorenz, independent journalist and former New York Times technology reporter. The …

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Science & Tech

Workday’s Last Workday? AI and the Future of Enterprise Software

Elena Berger speaks with Joe Schmidt IV, partner on the enterprise team at Andreessen Horowitz, about the vulnerability of entrenched enterprise software platforms. The conversation centers on Schmidt…

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The Shift in Global Drug Development

Cremieu Recoué, an independent researcher specializing in genetics, metrics, and demographics, joins MTS hosts Theo Jaffe and Gabriel Dickinson to discuss a dramatic shift in global biomedical innovat…

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John and Patrick Collison on Stripe's Growth, Agent Commerce, and the Future of Software

This conversation features John Coogan and Patrick Collison, co-founder and president of Stripe, discussing the company's latest announcements and economic trends. The discussion was recorded live on …

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Ben Horowitz on Venture Capital and AI

Ben Horowitz, co-founder of Andreessen Horowitz, speaks with Anjni Midha at Stanford's CS153 Frontiers class about revolutionizing venture capital structure and navigating the AI transformation. Horow…

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Science & Tech

AI Inside the Enterprise

Steven Sinofsky (board partner at A16Z), Aaron Levy (CEO of Box), and Martine Casado (general partner at A16Z) discuss the growing divide between AI capabilities in Silicon Valley and enterprise deplo…

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Martin Shkreli on AI, Pharma, and What Actually Matters

This episode features Martin Shkreli, American investor and businessman, discussing the current state of AI, hardware innovation, and pharmaceutical development. The conversation covers the competitiv…

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Balaji Srinivasan: Prove Correct, Not Just Go Direct

This episode features Balaji Srinivasan, author of The Network State, founder of NetworkSchool, and angel investor, speaking with A16Z General Partner Eric Torrenberg about the intersection of technol…

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Science & Tech

Marc Andreessen: Monitoring the Situation and the Future of Media

Mark Andreessen, co-founder and general partner at Andreessen Horowitz, joins Theo Jaffe on the inaugural episode of Monitoring the Situation (MTS), a new always-on media network covering tech, busine…

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Technology, Culture, and the Next AI Interface with signüll

This conversation features Signal, an online commentator known for his Shakespeare avatar and cultural analysis, alongside A16Z general partner Anisha Charya. Signal brings a unique perspective that b…

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Science & Tech

Replit's CEO on Vibe Coding, Wealth Building, and What Most People Get Wrong About AI

Amjad Masad is the CEO and founder of Replit, a company that democratizes software development by allowing anyone to build applications through AI without coding knowledge. Growing up in Jordan in a l…

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Science & Tech

Ben Horowitz on AI Infrastructure, Economics and The New Laws of Software

Ben Horowitz, co-founder and general partner at Andreessen Horowitz (A16Z), speaks with A16Z general partner Alex Rampell at the FinTech Connect Conference in Deer Valley. Horowitz brings decades of e…

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Science & Tech

Building Agents at Home: Parenting, Work, and Benevolent Neglect

Jesse Janae is a former Y Combinator founder who sold her venture-backed packaging company Lumi and now homeschools four children under six. She speaks with Catherine Boyle and Sarah Wang about her vi…

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Science & Tech

What Running Windows at Microsoft Taught Steven Sinofsky About Apple

Steven Sinofsky, board partner at A16Z and former president of Microsoft's Windows division, speaks with A16Z research partner Theo Jaffe about the 50th anniversary of Apple and the fundamental cultur…

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Science & Tech

Who Controls AI Acceleration? Vitalik Buterin and Guillaume Verdon Debate

This conversation features Vitalik Buterin, founder of Ethereum, Guillaume Verdon, founder and CEO of Extropic, Shaw Walters from Eliza Labs, and Eddie Lazarin, CTO of A16Z Crypto. The discussion cent…

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Science & Tech

The Agent Era: Building Software Beyond Chat with Box CEO Aaron Levie

Aaron Levy, CEO of Box, joins A16Z board partner Steve Sanofsky and A16Z general partner Martin Casado to discuss the enterprise implications of AI agents at scale. The conversation explores the funda…

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Science & Tech

Balaji on Why AI Raises the Cost of Verification

Balaji Srinivasan, angel investor and entrepreneur, discusses the economic and social implications of AI adoption, arguing that artificial intelligence fundamentally changes the cost structure of crea…

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Science & Tech

Peter Yang on Small Teams, Coding Agents, and Why Human Ambition Has No Ceiling

Anish Acharya, General Partner at A16Z, speaks with Peter Yang, Product Manager at Roblox and prolific creator on X and YouTube. Yang shares insights from his extensive experience with OpenClaw, an AI…

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Science & Tech

Marc Andreessen on AI Winters and Agent Breakthroughs

Mark Andreessen, co-founder and general partner at A16Z, discusses his perspective on the current AI revolution with Swix and Alessio Finelli from the Latent Space podcast. Andreessen brings a unique …

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Science & Tech

Alex Blania on Proof of Human and Building World's Identity Network

Alex Blanya, co-founder and CEO of World, joins A16Z co-founder and general partner Ben Horowitz to discuss the escalating challenge of distinguishing humans from AI agents online. World is building w…

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Science & Tech

What Happens When a Public Company Goes All In on AI

Owen Jennings serves as Executive Officer and Business Lead at Block, overseeing product operations and customer support across Square, Cash App, and Afterpay. Previously CEO of Cash App during its cr…

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Science & Tech

Marc Andreessen on Evaluating Founders and AI's Consumer Surplus

Harry Stebbings speaks with Mark Andreessen, co-founder of Andreessen Horowitz (A16Z), which manages over $90 billion and has invested in generational companies like Facebook. This conversation, origi…

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Science & Tech

The SpaceX and Tesla Playbook for Hard Tech Startups

Aaron Price-Wright speaks with Chandler Luzica, founder and CEO of Galadyne (next-generation missile propulsion), and Turner Caldwell, founder and CEO of Mariana Minerals (critical mineral supply chai…

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Science & Tech

Security, Resilience, and the Future of Mobile Infrastructure

This conversation features Justin Finelli, Chief Technology Officer of the Navy on his second tour, and John Doyle, founder and CEO of CAPE, a secure cellular network company. Finelli brings extensive…

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Science & Tech

Submarines and the Future of Defense Manufacturing

David Ulovich hosts a conversation with Chris Power, founder and CEO of Hadrian, and Vice Admiral Robert Goucher, the Pentagon's first submarine czar responsible for all U.S. Navy submarine production…

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Science & Tech

The Missing Power Layer of Modern Warfare

Aaron Price-Wright speaks with Adam Wormuth, founder and CEO of Chariot Defense, and Alex Miller, CTO of the U.S. Army. Adam previously led engineering at Anduril and product at Archer Aviation, while…

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Science & Tech

Why Every Satellite Needs Earth | Northwood CEO on a16z

Bridget Membler is co-founder and CEO of Northwood, a company building end-to-end ground infrastructure for space missions. She brings an unconventional background, having transitioned from entertainm…

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Science & Tech

Inside Palantir: Building Software That Matters with Shyam Sankar

Sham Sankar, Chief Technology Officer at Palantir Technologies and newly commissioned Army officer, joins A16Z general partner Catherine Boyle to discuss America's defense industrial transformation. S…

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Science & Tech

AI Just Gave You Superpowers — Now What?

Christian Catalini, co-founder of LightSpark and founder of the MIT Crypto Economics Lab, joins Eddie Lazarin, Chief Technology Officer at A16Z, to discuss Catalini's new economics paper analyzing the…

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Science & Tech

AI, Supply Chains, and the Future of Economic Power

Jacob Helberg, Under Secretary of State for Economic Affairs, discusses America's strategy to win the AI race at the A16Z American Dynamism Summit. Drawing from his 2021 book The Wires of War, Helberg…

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Science & Tech

What's Missing Between LLMs and AGI - Vishal Misra & Martin Casado

Martin Casado speaks with Vishal Misra, Professor and Vice Dean of Computing and AI at Columbia University, about his groundbreaking mathematical models of how large language models actually function.…

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Science & Tech

AI Startups vs. Big Chatbots — With Olivia Moore

Olivia Moore, AI partner at Andreessen Horowitz, joins Alex Kantrowitz on Big Technology Podcast to discuss whether startups can compete with dominant AI chatbots. Moore invests in AI applications and…

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Science & Tech

Marc Andreessen on the Mindset of Great Founders — with David Senra

Marc Andreessen, co-founder of Andreessen Horowitz and Netscape, joins David Senra on the Founders podcast for a wide-ranging conversation about entrepreneurship, technology, and building the future. …

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Science & Tech

Emil Michael: Iran, Anthropic and the Future of AI at the Pentagon

Emil Michael serves as Under Secretary of Defense for Research and Engineering and acting director of the Defense Innovation Unit. A Silicon Valley veteran who previously founded Tell Me Network (sold…

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Science & Tech

Palantir CEO Alex Karp on the Zero-Sum AI Race

Alex Karp, co-founder and CEO of Palantir, speaks at the A16Z American Dynamism Summit in Washington, D.C., following recent U.S. military operations in the Middle East that demonstrated unprecedented…

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Science & Tech

What It Takes to Clear a Million Crimes a Year with Flock Safety's CEO

Garrett Langley, founder and CEO of Flock Safety, discusses building America's largest crime-fighting technology platform with John Collison of Stripe. Langley, an electrical engineer, started the com…

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Science & Tech

The Top 100 Gen AI Consumer Apps

Anisha Charya, general partner at A16Z, interviews Olivia Moore, partner at A16Z, about the sixth edition of their Top 100 AI report covering global AI adoption trends and platform competition. The co…

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Science & Tech

Andrew Huberman: Peptides, Sleep Tech, and the End of Obesity

Dr. Andrew Huberman, professor of neurobiology and ophthalmology at Stanford University, joins A16Z partner Daisy Wolf to discuss the dramatic shift in consumer health behavior over the past five year…

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Science & Tech

Atlassian CEO on the SaaS Apocalypse, AI Agents & What Comes Next

Mike Cannon-Brooks, co-founder and CEO of Atlassian, joins Alex Rampell and the host to discuss the AI transformation of software and the so-called "SaaS apocalypse." The conversation explores how AI …

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Science & Tech

Ben Thompson: Anthropic, the Pentagon, and the Limits of Private Power

Ben Thompson, founder of Stratechery, joins John Kukin and Jordi Hayes to discuss his essay "Anthropic and Alignment" following the Department of War's designation of Anthropic as a supply chain risk.…

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Science & Tech

Ambience CEO Nikhil Buduma on AI in Clinical Workflows

Julie Yu, A16Z general partner, interviews Nikhil Buduma, CEO and co-founder of Ambience Healthcare, a company founded in 2020 that works with major academic medical centers to deploy AI-powered clini…

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Science & Tech

Ben Horowitz On What Makes a Great Founder

Ben Horowitz, co-founder and general partner at Andreessen Horowitz, speaks with Brian Halligan, partner at Sequoia Capital and former CEO of HubSpot. The conversation explores Horowitz's 15+ years of…

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Science & Tech

Chris Dixon: From Quant Trading to Building a16z Crypto

Chris Dixon, general partner at Andreessen Horowitz, traces his journey from 1980s programming prodigy to crypto fund pioneer. Dixon taught himself C and assembly language as a kid making video games,…

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Science & Tech

a16z's New Media Playbook

This episode features Ben Horowitz, Mark Andreessen, and Eric Newcomer discussing A16Z's comprehensive new media strategy at a recent All Hands meeting. The conversation covers the firm's transition f…

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Science & Tech

When Giants Don’t Go Public: Inside the $5 Trillion Private Tech Market

David George, General Partner and head of growth at Andreessen Horowitz (A16Z), joins Bloomberg's Odd Lots hosts Joe Weisenthal and Tracy Alloway to discuss the massive shift in how and when companies…

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Science & Tech

Ben Horowitz: RSI, Crypto as AI Money, & Classified Physics

Peter Diamandis hosts this Moonshots podcast episode with co-hosts Salim Ismail, Dave Blundin, and Dr. Alexander Wissner-Gross, joined by Ben Horowitz, co-founder and general partner at Andreessen Hor…

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Science & Tech

Patrick Collison on Stripe’s Early Choices, Smalltalk, and What Comes After Coding

Patrick Collison, CEO of Stripe, sits down with Michael Truel, CEO of Cursor, to discuss programming paradigms, development environments, and the intersection of AI with both software engineering and …

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Science & Tech

Capital, Compute, and the Fight for AI Dominance

Martin Casado and Sarah Wang, general partners at Andreessen Horowitz, discuss the unprecedented dynamics reshaping AI investing with Alessio Fanelli and Sean Wang from Latent Space podcast. Casado, w…

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Science & Tech

From Copilots to Agents: Rebuilding the Company Around AI

Carlos Garcia Otati, founder and CEO of Kavak, joins A16Z's Angela Strange and Gabriel Vasquez to discuss building Latin America's largest automotive e-commerce platform. Born in Caracas, Venezuela, C…

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Science & Tech

WSJ x a16z: The Next 25 Years of Defense Innovation

Katherine Boyle, General Partner at Andreessen Horowitz, discusses the firm's American Dynamism practice and the dramatic shift in Silicon Valley's approach to defense technology. The conversation exp…

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Science & Tech

Novartis CEO Vasant Narasimhan on Transforming a 250-Year-Old Company

Vasant Narasimhan, CEO of Novartis International since 2018, joins A16Z general partner Jorge Conde to discuss the transformation of the 250-year-old pharmaceutical giant. Narasimhan, a physician-scie…

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Science & Tech

Balaji and Dan Wang: The Engineering State vs Lawyerly State

Balaji Srinivasan speaks with Dan Wang, author of Breakneck, about the fundamental differences between China's engineering-focused state and America's lawyer-dominated system. Wang brings deep experie…

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Science & Tech

Anish Acharya: Is SaaS Dead in a World of AI?

Harry Stebbings interviews Anisha Charya, General Partner at Andreessen Horowitz, discussing the future of enterprise software, AI's impact on SaaS markets, and where startups versus incumbents will w…

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Science & Tech

How Magic Johnson Built a Billion-Dollar Portfolio in 30 Years

Magic Johnson, five-time NBA champion turned billion-dollar entrepreneur, sits down with Chris Lyons from Andreessen Horowitz to discuss his journey from basketball legend to business mogul. Johnson's…

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Science & Tech

Marc Andreessen: Who Runs the World’s AI?

Mark Andreessen, co-founder and general partner at Andreessen Horowitz and inventor of the web browser, speaks with G2 Patel, President and Chief Product Officer at Cisco, about the current AI landsca…

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Science & Tech

The State of Markets

David George, General Partner at Andreessen Horowitz, presents the firm's first comprehensive data analysis on AI company performance and market dynamics. The discussion covers both demand-side metric…

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Science & Tech

Balaji & Benedict Evans: When Tech Breaks Industries

Benedict Evans, independent technology analyst and newsletter author, joins Balaji Srinivasan on the Network State podcast from Singapore. Evans, who worked at Andreessen Horowitz over a decade ago, h…

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Science & Tech

Why This Isn't the Dot-Com Bubble | Martin Casado on WSJ's BOLD NAMES

Martin Casado, general partner at Andreessen Horowitz, discusses the current AI investment boom and whether it represents a dangerous bubble. Casado runs A16Z's billion-dollar infrastructure practice,…

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Science & Tech

Why America’s Health Crisis Is an Incentive Problem

Justin Maris is the founder and CEO of TrueMed, a company that allows people to spend tax-free HSA and FSA dollars on lifestyle interventions like gym memberships, better food, and sleep aids. He has …

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Science & Tech

Palmer Luckey on Hardware, Building, and the Next Frontiers of Innovation

This brief segment contains the standard legal disclaimer for A16Z podcast content, clarifying that discussions are not investment advice and noting potential conflicts of interest. The disclaimer dir…

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Science & Tech

David Solomon & Ben Horowitz on Building Organizational Resilience & Navigating Macro Uncertainty

This conversation features David Solomon, Chairman and CEO of Goldman Sachs (25+ years at the firm), and Ben Horowitz, co-founder of Andreessen Horowitz, moderated by A16Z general partner David Haber.…

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Science & Tech

“Anyone Can Code Now” - Netlify CEO Talks AI Agents

Matt Biilmann, CEO and founder of Netlify and creator of the Jamstack, joins A16Z general partner Martin Casado to discuss the dramatic transformation happening in web development. Biilmann coined the…

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Science & Tech

Marc Andreessen on Why This Is the Most Important Moment in Tech History

Mark Andreessen, co-founder of Andreessen Horowitz and creator of the first web browser, joins Lenny Rachitsky to discuss what he calls the most interesting year in his career. Andreessen has been rig…

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Science & Tech

Ben Horowitz and Balaji Srinivasan on Netscape and Network States

Ben Horowitz, co-founder of Andreessen Horowitz, joins Balaji Srinivasan on the Network State podcast to explore how internet-first institutions are forming and whether network states represent the ne…

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Science & Tech

Healthcare 2026: AI Doctors, GLP-1s, and Insurance Defection

Jay Rugani, partner at A16Z Health and Bio, sits down with Nikhil Krishnan, founder of Out of Pocket, to examine how consumer behavior, technology, and economics are converging to reconfigure U.S. hea…

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Science & Tech

The Hidden Economics Powering AI

A16Z's Jen Ka, head of investor relations, interviews David George, general partner, about how AI is reshaping technology markets and investment patterns. George leads A16Z's growth fund, which focuse…

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Science & Tech

How Mintlify Is Rebuilding Documentation for Coding Agents

This episode features Han Wang and Han Bi Li, co-founders of Mintlify, a documentation platform serving major companies like Anthropic, Microsoft, and Coinbase. They're joined by A16Z General Partner …

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Science & Tech

Martin Casado on the Demand Forces Behind AI

This episode features Martine Casado, General Partner at Andreessen Horowitz, where he runs the infrastructure fund focusing on compute, networking, storage, databases, AI infrastructure, dev tools, a…

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Science & Tech

The Secret Marketing Strategy That Built a16z: From Zero to Legendary VC Firm

The episode features Margaret Wennmachers, head of marketing at Andreessen Horowitz for 16 years, in conversation with co-founders Marc Andreessen and Ben Horowitz, discussing the firm's unconventiona…

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Science & Tech

Rocket Mortgage CEO: Here’s How to Fix the Housing Crisis

The episode features Alex (investor at Andreessen Horowitz and Rocket board member), Verun (CEO of Rocket Companies for two years, first outside CEO in company's 40-year history), and host discussing …

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Science & Tech

Grant Lee: Building Gamma’s AI Presentation Company to 100 Million Users

The episode features Grant Lee, co-founder and CEO of Gamma, one of the most successful AI applications with over 100 million users and $100 million in annual recurring revenue. Grant shares the journ…

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Science & Tech

Michael Truell: How Cursor Builds at the Speed of AI

The episode features Michael Troll, co-founder and CEO of Cursor, in conversation with general partner Martin Cassada at a conference. Cursor is one of the fastest-growing companies in the AI coding s…

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Science & Tech

Amjad Masad & Adam D’Angelo: How Far Are We From AGI?

The episode features Adam D'Angelo, co-founder of Quora and founder of Poe, alongside Amad Sabeti, founder and CEO of Replit, discussing the current state and future trajectory of AI development with …

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Science & Tech

Sacks, Andreessen & Horowitz: How America Wins the AI Race Against China

The episode features David Sacks, AI and Crypto Czar in the Trump administration, discussing regulatory approaches to emerging technologies and America's competitive position in AI development. Sacks …

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