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What How I Built This with Guy Raz Says About Entrepreneurship
29 episodes about entrepreneurship
<p>Guy Raz interviews the world’s best-known entrepreneurs to learn how they built their iconic brands. In each episode,...
Key Insights on Entrepreneurship
"Weird wins" - startups can thrive building products touching disagreement, persuasion, and sexuality that big tech committees explicitly avoid due to brand risk
- CMC (Chemical Manufacturing Controls) work is consistently underinvested in biotech startups, causing deal delays and requiring extensive rework by acquirers
- UK self-driving startup Wave raised $1.2 billion from Mercedes-Benz, Stellantis, and Nissan for London robo-taxi launch
- Small startups deploy AI "magically" while large enterprises struggle with risk-first approaches that prevent meaningful AI adoption
- 95% of LeadEdge's $3.5B fund comes from 800 world-class executives and entrepreneurs who provide sourcing, diligence, and customer introductions
- Peter Thiel invested $2.3 million in DeepMind, seeing Hassabis as an 'authentic missionary entrepreneur' destined for this mission
- SpaceX and Palantir alumni are founding the new wave of defense companies focused on national interest
- Most new crypto startups now build on Base, Arbitrum, or Solana rather than Ethereum mainnet due to better support and incentives
Episodes
Build-A-Bear: Maxine Clark. A Former Shoe Executive Launches a Stuffed Animal Empire
Advice Line with Christina Tosi of Milk Bar
Advice Line with Sarah LaFleur of M.M. LaFleur
Advice Line with Jonah Peretti of Buzzfeed
Beautycounter: Gregg Renfrew. She Built Beautycounter to $1B… Then Got Fired From Her Own Company
Advice Line with David Neeleman of JetBlue
Shep and Ian Murray: Vineyard Vines. A Stale Product Transforms into a Lifestyle Brand.
Advice Line with Eric Ryan of Method returns
Advice Line with Chieh Huang of Boxed
iRobot: Colin Angle. How The Roomba Became a Household Icon
Advice Line with Steve Ells of Chipotle
diapers.com: Marc Lore. The ecommerce visionary who lost to Amazon but still made billions (2021)
Advice Line with Marcia Kilgore of Beauty Pie (June 2025)
Vital Farms: Matt O’Hayer. How a serial entrepreneur re-branded the egg
Advice Line: What’s Your Value?
Scrub Daddy: Aaron Krause. How a Failed Experiment Became a Billion-Dollar Sponge
Advice Line with Hernan Lopez of Wondery
Bobo’s: Beryl Stafford. A Single Mom Turns a Baking Project into a $100M Business
Advice Line with Miguel McKelvey of WeWork
Kettle Chips: Cameron Healy. The Wild Bet That Made a Brand
Square: Jim McKelvey. He Lost a $2,000 Sale, Then Built a $10 Billion Company
Spinbrush: John Osher. The Electric Toothbrush That Sold for $475M
Advice Line with Julia Hartz of Eventbrite
Netflix: Reed Hastings. “We’re Not a Family.” The Provocative Idea That Helped Build a Streaming Giant
HOKA: Jean-Luc Diard and Nicolas Mermoud. The “Clown Shoe” That Became a $2B Bonanza
Advice Line with Serial Entrepreneur Mark Cuban
Advice Line with Monica Nassif of Mrs. Meyers
Gymboree: Joan Barnes. How Building a Beloved Brand Nearly Destroyed Its Founder
Advice Line with Jack Conte of Patreon (December 2024)
Books on entrepreneurship
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