Invest Like the Best with Patrick O'Shaughnessy

What Invest Like the Best with Patrick O'Shaughnessy Says About Artificial Intelligence

22 episodes about artificial intelligence

Key Insights on Artificial Intelligence

AI makes this Cold War more dangerous and unpredictable than the first one, despite nuclear weapons still existing

  • Competition drives innovation when nonviolent, as seen in AI and electric vehicles, but becomes dangerous when states compete militarily
  • FM Investments built an anti-hallucination large language model trained on 1,784 documents to simulate Fed candidate Kevin Warsh's policy positions.
  • The underlying AI technology exponential has progressed roughly as expected, moving from 'smart high school student to smart college student to beginning PhD level' - Dario
  • Clinical trials will accelerate but 'not instant, not infinitely fast' due to manufacturing and regulatory constraints even with AI drug discovery
  • AI models already write 90% of code lines at some companies, but productivity gains follow a spectrum from lines to full end-to-end tasks
  • Export controls on AI chips to China remain difficult to enforce despite bipartisan support due to economic pressures
  • Profitability in AI comes from accurately predicting demand rather than underinvesting, with inference margins exceeding 50%

Episodes

Vlad Barbalat - Investing $120 Billion in Permanent Capital - [Invest Like the Best, EP.479]

Vlad Barbalat - Investing $120 Billion in Permanent Capital - [Invest Like the Best, EP.479]

Gavin Baker - Watts and Wafers - [Invest Like the Best, EP.473]

Gavin Baker - Watts and Wafers - [Invest Like the Best, EP.473]

Krishna Rao - Anthropic's CFO on Compute, Scaling to $30B ARR, and the Returns to Frontier Intelligence - [Invest Like the Best, EP.471]

Krishna Rao - Anthropic's CFO on Compute, Scaling to $30B ARR, and the Returns to Frontier Intelligence - [Invest Like the Best, EP.471]

Brian Chesky - AI Founder Mode - [Invest Like the Best, EP.470]

Brian Chesky - AI Founder Mode - [Invest Like the Best, EP.470]

Paul Tudor Jones - Lessons From 50 Years in Markets - [Invest Like the Best, EP.469]

Paul Tudor Jones - Lessons From 50 Years in Markets - [Invest Like the Best, EP.469]

Dylan Patel - The Infinite Demand for Tokens, Claude Mythos, and Supply Constraints - [Invest Like the Best, EP.468]

Dylan Patel - The Infinite Demand for Tokens, Claude Mythos, and Supply Constraints - [Invest Like the Best, EP.468]

Alex Karnal - The Trillion-Dollar Health Revolution - [Invest Like the Best, EP.467]

Alex Karnal - The Trillion-Dollar Health Revolution - [Invest Like the Best, EP.467]

Scott Nolan - SpaceX, Founders Fund, and Rebuilding American Uranium Enrichment - [Invest Like the Best, EP.467]

Scott Nolan - SpaceX, Founders Fund, and Rebuilding American Uranium Enrichment - [Invest Like the Best, EP.467]

Alan Waxman - Private Credit and the Modern Financial System - [Invest Like the Best, EP.466]

Alan Waxman - Private Credit and the Modern Financial System - [Invest Like the Best, EP.466]

Mitchell Green - Lessons from Cold Calling 10,000 Companies - [Invest Like the Best, EP.464]

Mitchell Green - Lessons from Cold Calling 10,000 Companies - [Invest Like the Best, EP.464]

William Hockey - Building the Operating System for the Dollar and Silicon Valley Heresy - [Invest Like the Best, EP.463]

William Hockey - Building the Operating System for the Dollar and Silicon Valley Heresy - [Invest Like the Best, EP.463]

Shyam Sankar - Celebrating Heretics - [Invest Like the Best, EP.462]

Shyam Sankar - Celebrating Heretics - [Invest Like the Best, EP.462]

John Arnold - China, Energy Markets and Fixing America's Systems - [Invest Like the Best, EP.461]

John Arnold - China, Energy Markets and Fixing America's Systems - [Invest Like the Best, EP.461]

Dan Sundheim - The Art of Public and Private Market Investing - [Invest Like the Best, EP.460]

Dan Sundheim - The Art of Public and Private Market Investing - [Invest Like the Best, EP.460]

Josh Kushner - Concentration and Conviction - [Invest Like the Best, EP.459]

Josh Kushner - Concentration and Conviction - [Invest Like the Best, EP.459]

Ben Horowitz - Backing America’s Future - [Invest Like the Best, EP.457]

Ben Horowitz - Backing America’s Future - [Invest Like the Best, EP.457]

Gokul Rajaram - Lessons from Investing in 700 Companies - [Invest Like the Best, EP.456]

Gokul Rajaram - Lessons from Investing in 700 Companies - [Invest Like the Best, EP.456]

Tom Digan & Greg Stewart - Building the World’s Best Fitness App - [Invest Like the Best, EP.454]

Tom Digan & Greg Stewart - Building the World’s Best Fitness App - [Invest Like the Best, EP.454]

Reed Hastings - Building Netflix - [Invest Like the Best, EP.453]

Reed Hastings - Building Netflix - [Invest Like the Best, EP.453]

Henry Ellenbogen - Man Versus Machine - [Invest Like the Best, EP.452]

Henry Ellenbogen - Man Versus Machine - [Invest Like the Best, EP.452]

Gavin Baker - Nvidia v. Google, Scaling Laws, and the Economics of AI - [Invest Like the Best, EP.451]

Gavin Baker - Nvidia v. Google, Scaling Laws, and the Economics of AI - [Invest Like the Best, EP.451]

Josh Kushner - Building Thrive Capital - [Invest Like the Best, CLASSICS]

Josh Kushner - Building Thrive Capital - [Invest Like the Best, CLASSICS]

Books on artificial intelligence

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