a16z

What a16z Says About Science

26 episodes about science

a16z is a venture capital firm that invests in software eating the world. Each week, we share videos on technology trend...

Key Insights on Science

"Mask up in between bites" on airplanes should have been the moment everyone realized COVID protocols were theater, not science - Adam

  • Research proposal involves 25 cerebral palsy patients over five years to test replicability of the transformation method
  • What to Make of a Life took Collins 12 years of research studying pairs of notable figures who faced similar 'cliff events' that forced life reconstruction
  • Research shows perceived inequality drives political radicalization more than actual inequality, with social media amplifying wealth exposure effects
  • Political efficacy research shows reducing polarization doesn't reduce violence support, but belief in democratic channels working does
  • UBI proposals may backfire by confirming economic decline fears rather than addressing trajectory concerns, according to sacred values research
  • OpenClaw research agent operates 24/7 to hunt for new AI use cases and categorize them as Primetime, Emerging, or Frontier
  • AI models have crossed from creative parlor tricks into genuine reasoning, solving problems in medicine, law, and science that seemed impossible 18 months ago

Episodes

Before Blockchains, There Was State Machine Replication

Before Blockchains, There Was State Machine Replication

Jake Paul & Anti Fund: From Creator to Investor

Jake Paul & Anti Fund: From Creator to Investor

Designing the Physical World with AI

Designing the Physical World with AI

How Superhuman Took Over Silicon Valley Email

How Superhuman Took Over Silicon Valley Email

Crypto Fund 5: We Raised $2.2B. Here’s Why.

Crypto Fund 5: We Raised $2.2B. Here’s Why.

The New Space Race: NASA, Artemis, and the Race to the Moon

The New Space Race: NASA, Artemis, and the Race to the Moon

The Shift in Global Drug Development

The Shift in Global Drug Development

Technology, Culture, and the Next AI Interface with signΓΌll

Technology, Culture, and the Next AI Interface with signΓΌll

Building Agents at Home: Parenting, Work, and Benevolent Neglect

Building Agents at Home: Parenting, Work, and Benevolent Neglect

What Running Windows at Microsoft Taught Steven Sinofsky About Apple

What Running Windows at Microsoft Taught Steven Sinofsky About Apple

Who Controls AI Acceleration? Vitalik Buterin and Guillaume Verdon Debate

Who Controls AI Acceleration? Vitalik Buterin and Guillaume Verdon Debate

Balaji on Why AI Raises the Cost of Verification

Balaji on Why AI Raises the Cost of Verification

Marc Andreessen on AI Winters and Agent Breakthroughs

Marc Andreessen on AI Winters and Agent Breakthroughs

What's Missing Between LLMs and AGI - Vishal Misra & Martin Casado

What's Missing Between LLMs and AGI - Vishal Misra & Martin Casado

Emil Michael: Iran, Anthropic and the Future of AI at the Pentagon

Emil Michael: Iran, Anthropic and the Future of AI at the Pentagon

The Top 100 Gen AI Consumer Apps

The Top 100 Gen AI Consumer Apps

Andrew Huberman: Peptides, Sleep Tech, and the End of Obesity

Andrew Huberman: Peptides, Sleep Tech, and the End of Obesity

Ambience CEO Nikhil Buduma on AI in Clinical Workflows

Ambience CEO Nikhil Buduma on AI in Clinical Workflows

Ben Horowitz: RSI, Crypto as AI Money, & Classified Physics

Ben Horowitz: RSI, Crypto as AI Money, & Classified Physics

Patrick Collison on Stripe’s Early Choices, Smalltalk, and What Comes After Coding

Patrick Collison on Stripe’s Early Choices, Smalltalk, and What Comes After Coding

Novartis CEO Vasant Narasimhan on Transforming a 250-Year-Old Company

Novartis CEO Vasant Narasimhan on Transforming a 250-Year-Old Company

Why America’s Health Crisis Is an Incentive Problem

Why America’s Health Crisis Is an Incentive Problem

Marc Andreessen on Why This Is the Most Important Moment in Tech History

Marc Andreessen on Why This Is the Most Important Moment in Tech History

Ben Horowitz and Balaji Srinivasan on Netscape and Network States

Ben Horowitz and Balaji Srinivasan on Netscape and Network States

Healthcare 2026: AI Doctors, GLP-1s, and Insurance Defection

Healthcare 2026: AI Doctors, GLP-1s, and Insurance Defection

The Hidden Economics Powering AI

The Hidden Economics Powering AI

Books on science

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